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R45 | The Complete Reversal

Patented 4-phase treatments that target face and neck to tighten, brighten & sculpt ($364 Value)

or 4 installments of $72.25 USD by Info

Transform the look of your skin with R45’s patented technology and the power of titration therapy, carefully formulated to target your face and neck for pro-grade results in just 45 days. Our 4-phase anti-aging booster system is clinically proven to repair the 4 benchmarks of aging from the comfort of home – R45 The Reversal's TriGLO™ retinol complex helps combat discoloration, diminishes the look of fine lines and wrinkles, visibly reduces the appearance of enlarged pores and uneven texture. Powered by a proprietary AHA blend, The Lift's formula is designed to help sculpt the neck area for a more defined jawline. Both treatment ingredient concentrations gradually increase with each phase for a more youthful-looking appearance without the harsh side effects.


  • Smooths Wrinkles
  • Tightens Pores
  • Helps Prevent Tech Neck

Key Ingredients


Concentrations of our proprietary retinol complex gradually increase with each phase for a clinically proven reduction in the appearance of wrinkles, skin tone unevenness, skin spots and pore size.

Growth Factor Stimulant Serum

Peptide complex that strengthens skin’s proteins, increases hydration levels and fortifies skin against free radical damage.

Citric Acid

Helps stimulate collagen production and works to diminish dark spots.

Safflower Seed Oil

Combines with skin's sebum to unclog pores, reduce breakouts, and create a protective barrier to retain moisture.


Clinical Results


In a R45 The Reversal consumer perception survey:

100% agreed skin looked better once treatment was completed

95% noticed a visible change in skin

90% felt pores were less noticeable

90% felt skin looked more radiant

90% noticed a reduction in the appearance of wrinkles

In a consumer perception survey after completing all 3 phases of The Lift:

100% saw an improvement in the texture of their skin

93% felt the skin on their neck and décolleté appeared firmer

97% agreed their skin appeared smoother

93% noticed an improvement in crepiness

83% noticed a decrease in the appearance of fine lines and wrinkles

Before and After image of R45 The Reversal
Before and After image of R45 The Reversal
Before and After image of R45 The Reversal

R45 - a miracle worker!

- GA

              How to use R45 The Reversal

How To Use

For PM use. Cleanse face and neck. Pat dry. Apply 1-2 pumps of R45 The Reversal Phase 1 (Side A) + GFS Serum (Side B) to face. Then, apply 1-2 pumps of R45 The Lift Phase 1 to neck massaging in upward motions. Follow with your favorite moisturizer. After completing Phase 1 of The Reversal and The Lift, advance to Phase 2 and 3, and conclude with Phase 4. To maintain results, start again from Phase 1 as needed.

Warning: For external use only. Avoid direct eye contact. Discontinue use if irritation occurs. Do not use if pregnant or nursing. Sunburn alert: Use sunscreen, wear protective clothing and limit sun exposure while using this product and for a week afterwards.

Frequently Asked Questions

R45 results are so good, you only need to boost twice a year. Have some problem areas you’d like to target? You can definitely boost more often. When using R45 The Reversal, temporarily press pause on your other nighttime serums, as the treatment will deliver all results without assistance.

One of the best features of R45 is the step-up concentration found in each progressive phase. This patented formula allows your skin to ease into each phase even while using GloPRO®. For extremely sensitive skin types, perform a patch test first before using both R45 and GloPRO® together.

We encourage people to ask “what kind of retinol” instead of “how much”. Our proprietary retinol compound is a blend of retinyl, retinol and a retinoid (all forms of Vitamin A). Concentrations in each phase of R45 The Reversal increase by 50%, so Phase 2 is 50% stronger than Phase 1, and Phase 3 is 100% stronger than Phase 1. The true litmus test of a retinol’s efficacy is color. Retinol in its raw form is yellow, so if it isn’t yellow, it doesn’t contain enough of this key active to work.

Once you’ve completed Phase 3 of R45 The Reversal, we suggest switching over to a retinol-based serum to keep your results glowing strong. Our fave is The Nightly Retinol + Peptide Repair Serum. It maintains results in between R45 boosts.

We advise against using R45 The Reversal while pregnant and nursing because of the high concentration of retinol within the product.

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