Cleanse face and pat dry.
Apply 1-2 pumps of R45 The Reversal Phase 1 Regeneration Complex (Side A) + GFS Serum (Side B) to face.
After R45 The Reversal Phase 1 is complete, advance to Phase 2 and conclude with Phase 3. Results are cumulative, do not start with Phase 2 or Phase 3.
Follow with your favorite moisturizer.
For PM use.
Concentrations of our deep-release retinol complex increase with each phase for a clinically proven reduction in the appearance of wrinkles, skin tone unevenness, skin spots and pore size.
Peptide complex that strengthens skin’s proteins, increases hydration levels and fortifies skin against free radical damage.
Helps stimulate collagen production and works to diminish dark spots.
Combines with skin's sebum to unclog pores, reduce breakouts, and create a protective barrier to retain moisture.
View All Ingredients
REGENERATION COMPLEX: WATER, COCOGLYCERIDES, SAFFLOWER ACIDS, TOCOPHERYL ACETATE, ACRYLATES/C 10-30 ALKYL ACRYLATE CROSSPOLYMER, SODIUM HYALURONATE, LYSOLECITHIN, RETINOL, GLYCERYL DIRETINOATE, GLYCERYL 10 LAURATE, RETINYL PALMITATE, CITRIC ACID, BHT, ACETYL CARBOXYMETHYL COCOYL GLYCINATE, SAFFLOWER GLYCERIDES, TOCOPHERYL ACETATE, CAPRYLYL GLYCOL, PHENOXYETHANOL. GFS SERUM: WATER, GLYCERIN, BUTYLENE GLYCOL, CYCLOPENTASILOXANE, PENTYLENE GLYCOL, PEG-12 DIMETHICONE CROSSPOLYMER, DIMETHICONE CROSSPOLYMER, DIMETHICONE/VINYL DIMETHICONE CROSSPOLYMER, SODIUM POLYACRYLATE, DIMETHICONE, PEG/PPG-18 / 18 DIMETHICONE, DIMETHICONOL, SODIUM HYALURONATE, CAMELLIA SINENSIS EXTRACT, DISODIUM EDTA COPPER, MYRISTOYL PENTAPEPTIDE 17, HYDROXYPHENYL PROPAMIDOBENZOIC ACID, BISABOLOL, ZINGIBER OFFICINALE (GINGER) ROOT EXTRACT, POLYSORBATE 60, CAPRYLYL GLYCOL, PHENOXYETHANOL.
Smooth fine lines & wrinkles - Clinically proven to reduce the appearance of wrinkles by an average of 49.5% in 45 days
Tighten enlarged pores
Erase dark & age spots - Assists in collagen production and diminishes the appearance of dark spots and age spots
Repair uneven skin tone
R45 results are so good, you only need to boost twice a year. Have some problem areas you’d like to target? You can definitely boost more often. When using R45 The Reversal, temporarily press pause on your other nighttime serums, as the treatment will deliver all results without assistance.
One of the best features of R45 is the step-up concentration found in each progressive phase. This patented formula allows your skin to ease into each phase even while using GloPRO®. For extremely sensitive skin types, perform a patch test first before using both R45 and GloPRO® together.
We encourage people to ask “what kind of retinol” instead of “how much”. Our proprietary retinol compound is a blend of retinyl, retinol and a retinoid (all forms of Vitamin A). Concentrations in each phase of R45 The Reversal increase by 50%, so Phase 2 is 50% stronger than Phase 1, and Phase 3 is 100% stronger than Phase 1. The true litmus test of a retinol’s efficacy is color. Retinol in its raw form is yellow, so if it isn’t yellow, it doesn’t contain enough of this key active to work.
Once you’ve completed Phase 3 of R45 The Reversal, we suggest switching over to a retinol-based serum to keep your results glowing strong. Our fave is The Nightly Retinol + Peptide Repair Serum. It maintains results in between R45 boosts.
We advise against using R45 The Reversal while pregnant and nursing because of the high concentration of retinol within the product.
In a clinical study using VISIA facial skin scan analysis, R45 The Reversal achieved a measured 49.5% reduction in the appearance of fine lines and deep mechanical wrinkles.
In a consumer perception survey: