R45 | The Reversal
Patented 3-phase retinol night cream that tightens, brightens, smooths and corrects
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Our award-winning R45 The Reversal anti-aging retinol night cream utilizes a patented booster system that is so powerful, you only need to use it twice a year. In just 45 days, this 3-phase treatment is clinically proven to repair all 4 benchmarks of aging – discoloration, wrinkles, enlarged pores and uneven texture. Our proprietary retinol complex, TriGLO™, mimics the skin-smoothing effects of clinical retinol without the harsh side effects. Finally, an over-the-counter retinol every skin type can use. Take the #R45DayChallenge and see for yourself!
Step 1
Cleanse face and pat dry.
Step 2
Apply 1-2 pumps of R45 The Reversal Phase 1 Regeneration Complex (Side A) + GFS Serum (Side B) to face.
Step 3
After R45 The Reversal Phase 1 is complete, advance to Phase 2 and conclude with Phase 3. Results are cumulative, do not start with Phase 2 or Phase 3.
Step 4
Follow with your favorite moisturizer.
For PM use.
Skinsider Tips:
- Boost skin with R45 The Reversal 2x a year.
- While boosting, take a vacation from other PM treatment serums.
- For maximum results, use GloPRO® FACE MicroTip™ before applying R45 The Reversal.
- Avoid direct eye contact.
TriGLO®
Concentrations of our deep-release retinol complex increase with each phase for a clinically proven reduction in the appearance of wrinkles, skin tone unevenness, skin spots and pore size.
Growth Factor Stimulant Serum
Peptide complex that strengthens skin’s proteins, increases hydration levels and fortifies skin against free radical damage.
Citric Acid
Helps stimulate collagen production and works to diminish dark spots.
Safflower Seed Oil
Combines with skin's sebum to unclog pores, reduce breakouts, and create a protective barrier to retain moisture.
View All Ingredients
Phase 1-3: WATER/AQUA/EAU, SAFFLOWER ACID, COCOGLYCERIDES, RETINOL, TOCOPHERYL ACETATE, SAFFLOWER GLYCERIDE, GLYCERYL DIRETINOATE, LYSOLECITHIN, SODIUM HYALURONATE, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, CAPRYLYL GLYCOL, ACETYL CARBOXYMETHYL COCOYL GLYCINE, POLYGLYCERYL-10 LAURATE, PHENOXYETHANOL, CITRIC ACID, BHT GFS Serum: WATER/AQUA/EAU, GLYCERIN, DIPROPYLENE GLYCOL, PROPYLENE GLYCOL, CYCLOPENTASILOXANE, PEG-12 DIMETHICONE CROSSPOLYMER, DIMETHICONE CROSSPOLYMER, DIMETHICONE/VINYL DIMETHICONE CROSSPOLYMER, DIMETHICONOL, BUTYLENE GLYCOL, PENTYLENE GLYCOL, HYDROXYPHENYL PROPAMIDOBENZOIC ACID, SODIUM HYALURONATE, MYRISTOYL PENTAPEPTIDE-17, CAPRYLYL GLYCOL, SODIUM POLYACRYLATE, TRIDECETH-6, POLYSORBATE 60, PEG/PPG-18/18 DIMETHICONE, DISODIUM EDTA-COPPER, DIMETHICONE, PHENOXYETHANOL
Smooth fine lines & wrinkles - Clinically proven to reduce the appearance of wrinkles by an average of 49.5% in 45 days
Tighten enlarged pores
Erase dark & age spots - Assists in collagen production and diminishes the appearance of dark spots and age spots
Repair uneven skin tone
How often should I use R45 The Reversal?
R45 results are so good, you only need to boost twice a year. Have some problem areas you’d like to target? You can definitely boost more often. When using R45 The Reversal, temporarily press pause on your other nighttime serums, as the treatment will deliver all results without assistance.
Can I use R45 The Reversal and GloPRO® together?
One of the best features of R45 is the step-up concentration found in each progressive phase. This patented formula allows your skin to ease into each phase even while using GloPRO®. For extremely sensitive skin types, perform a patch test first before using both R45 and GloPRO® together.
What is the percentage of retinol in each of the phases of R45 The Reversal?
We encourage people to ask “what kind of retinol” instead of “how much”. Our proprietary retinol compound is a blend of retinyl, retinol and a retinoid (all forms of Vitamin A). Concentrations in each phase of R45 The Reversal increase by 50%, so Phase 2 is 50% stronger than Phase 1, and Phase 3 is 100% stronger than Phase 1. The true litmus test of a retinol’s efficacy is color. Retinol in its raw form is yellow, so if it isn’t yellow, it doesn’t contain enough of this key active to work.
What skincare do I use after completing R45 The Reversal?
Once you’ve completed Phase 3 of R45 The Reversal, we suggest switching over to a retinol-based serum to keep your results glowing strong. Our fave is The Nightly Retinol + Peptide Repair Serum. It maintains results in between R45 boosts.
Can I use R45 The Reversal while pregnant or breastfeeding?
We advise against using R45 The Reversal while pregnant and nursing because of the high concentration of retinol within the product.
In a clinical study using VISIA facial skin scan analysis, R45 The Reversal achieved a measured 49.5% reduction in the appearance of fine lines and deep mechanical wrinkles.
In a consumer perception survey:
- 100% agreed skin looked better once treatment was completed
- 95% noticed a visible change in skin
- 90% felt pores were less noticeable
- 90% felt skin looked more radiant
- 90% noticed a reduction in the appearance of wrinkles
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Frequently Asked Questions
R45 results are so good, you only need to boost twice a year. Have some problem areas you’d like to target? You can definitely boost more often. When using R45 The Reversal, temporarily press pause on your other nighttime serums, as the treatment will deliver all results without assistance.
One of the best features of R45 is the step-up concentration found in each progressive phase. This patented formula allows your skin to ease into each phase even while using GloPRO®. For extremely sensitive skin types, perform a patch test first before using both R45 and GloPRO® together.
We encourage people to ask “what kind of retinol” instead of “how much”. Our proprietary retinol compound is a blend of retinyl, retinol and a retinoid (all forms of Vitamin A). Concentrations in each phase of R45 The Reversal increase by 50%, so Phase 2 is 50% stronger than Phase 1, and Phase 3 is 100% stronger than Phase 1. The true litmus test of a retinol’s efficacy is color. Retinol in its raw form is yellow, so if it isn’t yellow, it doesn’t contain enough of this key active to work.
Once you’ve completed Phase 3 of R45 The Reversal, we suggest switching over to a retinol-based serum to keep your results glowing strong. Our fave is The Nightly Retinol + Peptide Repair Serum. It maintains results in between R45 boosts.
We advise against using R45 The Reversal while pregnant and nursing because of the high concentration of retinol within the product.
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